Comprehensive Medical Science Liaison Inquiry Documentation System

1. Section 1: Healthcare Professional (HCP) & Product Identifiers - Establishing Interaction Context

This section captures essential details about the Healthcare Professional and product to establish proper identification and interaction context. All fields marked mandatory must be completed to ensure regulatory compliance and accurate record-keeping.


HCP Full Name

Professional Credentials & Degrees

Primary Medical Specialty

Subspecialty (if applicable)

Practice Setting Environment

Geographic Region/Location


Professional Registration/License Number

Professional Email Address

Contact Phone Number

Years of Clinical Practice

Has this HCP interacted with our Medical Affairs team in the past 12 months?


Product & Indication Details

Product Brand Name

Generic Name/Active Ingredient

Formulation & Strength

Approved Regulatory Indication

Off-Label Use Being Discussed (if applicable)

ExampleBrand
exampleumab
IV infusion 100mg
Rheumatoid Arthritis
Systemic Lupus Erythematosus
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Interaction Channel

Interaction Date & Time

Interaction Duration

2. Section 2: Detailed Medical Inquiry & Patient Outcome Context - Clinical Scenario Documentation

Comprehensive documentation of the clinical inquiry and patient context is essential for medical assessment. Provide detailed yet de-identified patient information to support medical affairs review while maintaining patient privacy standards.


Primary Category of Medical Inquiry

Detailed Clinical Scenario & Medical Question

De-Identified Patient Demographics & Baseline Characteristics

Parameter

Value or Range

Clinical Relevance & Notes

Age Range
45-55 years
Patient in prime working age, compliance concerns
Gender
Female
Relevant for pregnancy considerations
Weight Range
70-80 kg
Within normal BMI range
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Relevant Medical History & Comorbidities

Prior Treatment History & Previous Therapies

Concomitant Medications & Non-Drug Therapies

Current Treatment Regimen with Product

Specific Patient Outcomes & Clinical Observations

Timeline of Key Clinical Events

Clinical Impact Assessment - Rate the following aspects of this inquiry

Very Low

Low

Moderate

High

Very High

Medical significance to patient care

Scientific complexity

Urgency of response needed

Potential for clinical practice impact

3. Section 3: Off-Label Information Dissemination & Fair-Balance Verification - Compliance Documentation

This section ensures regulatory compliance by documenting the unsolicited nature of the inquiry and verifying that fair balance was maintained when discussing off-label uses. Complete all fields meticulously as this information may be subject to regulatory inspection.


Was this inquiry completely unsolicited by the MSL or company?


Specific Off-Label Use or Investigational Context Discussed

Did the MSL provide any information regarding the off-label use?


Fair-Balance Documentation - How were risks, limitations, and approved alternatives presented?

Types of Scientific Materials Referenced or Shared (select all that apply)

Were all shared materials previously reviewed and approved by Medical Affairs?


Did the MSL make any commitments for follow-up actions or additional information?


Key Literature References or Data Sources Cited During Discussion

Compliance Risk Self-Assessment - Rate each compliance parameter

Clarity of unsolicited nature

Fair balance achieved

Appropriate scope of information

Avoidance of promotional language

Documentation completeness

4. Section 4: Pharmacovigilance & Adverse Event Safety Reporting Log - Patient Safety Documentation

Patient safety is paramount. This section must be completed for ANY inquiry involving adverse events, side effects, or unexpected outcomes. Timely and accurate reporting is essential for regulatory compliance and patient protection.


Does this inquiry involve a potential Adverse Event (AE) or unexpected side effect?


Is this a serious adverse event based on regulatory criteria?


Causality Assessment - Relationship to Product

AE Onset Date

Treatment Duration Before AE Onset

Relevant Medical History & Risk Factors

Action Taken with Product After AE

Outcome of the Adverse Event

Reporter Information for AE

Reporter Name

Relationship to Patient

Contact Information

Is reporter a Healthcare Professional?

Dr. Smith
Treating Physician
dr.smith@clinic.org
Yes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Was this AE reported to Company Pharmacovigilance within 24 hours?


Additional Safety Observations or Patterns Noted

5. Section 5: Medical Affairs Director Review & Approval - Workflow & Governance

This final section ensures appropriate oversight and governance of medical inquiries. All off-label discussions and AE reports require director-level review and approval before closure.


MSL Initial Risk Assessment - Overall Risk Level

MSL Summary & Recommendation

Does this inquiry pass initial compliance and policy check?


Is Medical Affairs Director review and approval required?


Date Submitted for Director Review

Director Approval Status

Medical Affairs Director Comments & Decision Rationale

Required Follow-Up Actions (select all that apply)

Does this require escalation to Drug Safety Committee?

Should this inquiry be shared with Global Medical Affairs network?

Key Scientific References & Evidence Sources for Response

Upload Supporting Documentation - Notes, Publications, or Relevant Materials

Choose a file or drop it here
 

MSL Digital Signature & Attestation

Final Form Completion Date & Time

This form is a silent disco… your edits? You just cranked up the music! 🎧💃 Edit this MSL Medical Inquiry & Pharmacovigilance Intake Form
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