Chain-of-Custody Request: Biological Material Transfer Between Research Facilities

1. Section 1: Material Identification & Biological Agent Risk Group Classification

Provide comprehensive identification and risk characterization for all biological materials proposed for transfer. Accurate classification is critical for determining packaging, transport, and containment requirements.


Primary Sample Material ID Number

Additional Sample Alias or Internal Tracking Code

Scientific Name of Biological Agent (Genus and Species)

Strain Designation or Isolate Identifier

WHO Risk Group Classification


Does this material contain genetically modified organisms (GMOs) or recombinant nucleic acids?


Is this agent known to produce toxins or biologically active metabolites?


Does this agent exhibit zoonotic potential or cross-species transmission capability?


Estimated Infectious Dose (ID50) in laboratory model if known

Infectious Dose Unit

Has this material been inactivated or attenuated?


Brief description of material composition and matrix

Total volume or mass of material to be transferred

Volume/Mass Unit

Number of individual containers/vials in shipment

Does material require any special handling beyond standard BSL practices?


2. Section 2: Sending & Receiving Facility Identification & Principal Investigator Credentials

Complete identification and verification of all facilities and responsible personnel involved in the transfer. International transfers require additional documentation.


Sending Institution/Laboratory Full Legal Name

Sending Facility Complete Physical Address

Sending Facility BSL Level Certification

Sending Principal Investigator Full Name

Sending PI Professional Title/Position

Sending PI Email Address

Sending PI Direct Phone/24-Hour Emergency Contact

Sending Facility Biosafety Officer Name

Sending Facility BSO Email and Phone

Is this an international transfer across national borders?


Receiving Institution/Laboratory Full Legal Name

Receiving Facility Complete Physical Address

Receiving Facility BSL Level Certification

Receiving Principal Investigator Full Name

Receiving PI Professional Title/Position

Receiving PI Email Address

Receiving PI Direct Phone/24-Hour Emergency Contact

Receiving Facility Biosafety Officer Name

Receiving Facility BSO Email and Phone

Has the receiving facility confirmed BSL compatibility and adequate containment capabilities?


3. Section 3: Containment, Cold-Chain Maintenance & Triple Packaging System Inspection

Verify complete compliance with triple packaging system requirements and cold-chain integrity. All packaging must meet UN standards for infectious substance transport.


Primary Container Type (Leak-proof Primary Receptacle)

Primary Container Material and Volume Capacity

Is primary container individually wrapped in absorbent material?


Secondary Packaging Type (Water-tight Leak-proof Receptacle)

Secondary Packaging UN Certification Number

Does secondary packaging contain sufficient absorbent for all primary containers?

Outer Packaging Type (Rigid Protective Outer Receptacle)

Outer Packaging UN Specification Marking

Is complete triple packaging system certified for air transport (IATA PI 620 or PI 650)?


Temperature Maintenance Requirements During Transit





Is a temperature monitoring device (data logger) included in shipment?


Have all exterior surfaces of outer packaging been decontaminated?


Are complete shipping documents externally attached in document pouch?


I certify that packaging has been inspected and meets all triple packaging system requirements

4. Section 4: Transport Transit Route, Carrier Specifications & Emergency Spill Contingency Protocols

Detailed transport logistics and emergency response preparedness are mandatory for all biological material transfers, especially for Risk Group 3 and 4 agents.


Primary Mode of Transport



Carrier Company Name and Account Number

Carrier Emergency Contact Number (24-hour)

Scheduled Shipment Departure Date and Time

Estimated Total Transit Duration (hours)

Will shipment transit through intermediate handling facilities or customs checkpoints?


Is shipment equipped with GPS real-time tracking?


EMERGENCY SPILL CONTINGENCY - Complete for all Risk Group 2, 3, and 4 materials


Has a written Emergency Action Plan (EAP) been provided to carrier?


Spill Response Kit Contents and Location During Transit

24-Hour Emergency Contact for Spill Response (Primary)

24-Hour Emergency Contact for Spill Response (Secondary)

Nearest Qualified Decontamination Facility to Transit Route

Has carrier personnel received biohazard spill response training?


Communication Protocol in Case of Transit Delay, Temperature Excursion, or Spill Event

Are there any geopolitical restrictions or sanctions affecting this transfer route?


5. Section 5: Institutional Biosafety Committee (IBC) Clearance, Risk Assessment & Final Authorization Sign-Off

Final authorization requires documented IBC approval, comprehensive risk assessment, and sign-off from all responsible authorities. Transfer cannot proceed without complete documentation.


Sending Facility IBC Approval Reference Number

Sending Facility IBC Approval Date

Sending Facility IBC Approval Expiration Date


Does sending IBC approval specifically authorize this material transfer?


Receiving Facility IBC Approval Reference Number

Receiving Facility IBC Approval Date

Receiving Facility IBC Approval Expiration Date

Does receiving IBC approval specifically authorize receipt and possession of this agent?


Has a comprehensive Material Transfer Agreement (MTA) been executed between institutions?


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Does this transfer involve any dual-use research of concern (DURC) considerations?


Have all personnel involved in packaging and transport received agent-specific safety training?


Final Packaging Inspection and Sign-off Timestamp

I certify that all information provided is accurate and complete to the best of my knowledge

I acknowledge that incomplete or inaccurate information may result in transport delays, regulatory violations, or biosafety incidents

I confirm that emergency response procedures have been communicated to all parties and are readily accessible during transit

Sending Principal Investigator Digital Signature

Sending Facility Biosafety Officer Digital Signature

Receiving Principal Investigator Digital Signature (Pre-receipt Acknowledgment)

Receiving Facility Biosafety Officer Digital Signature (Pre-receipt Verification)

Final IBC Administrative Review and Authorization Timestamp

Institutional Biosafety Committee Chair or Designated Reviewer Signature

Final Authorization Reference Code

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