Clinical Inquiry Intake: Unsolicited Off-Label Questions from Healthcare Professionals

1. Section 1: Field Representative & Healthcare Practitioner Metadata - Comprehensive Identification and Interaction Context Documentation

This section captures essential identification details about the field representative and the healthcare practitioner to ensure proper attribution, compliance tracking, and relationship context. Accurate metadata is critical for audit trails and regulatory inspection readiness.

 

Field Representative Employee ID

Field Representative Full Name

Field Representative Official Email

Field Representative Direct Phone Number

Field Representative Geographic Region

Date and Time of Interaction with Healthcare Practitioner

Interaction Setting/Context

 

Please specify other interaction setting:

Healthcare Practitioner Full Name

Healthcare Practitioner Primary Credential

Healthcare Practitioner Medical Specialty/Area of Practice

Healthcare Practitioner Institution/Practice Name

Institution Type

Institution Country

Institution State/Province

Institution City

Duration of Professional Relationship with this Healthcare Practitioner

Estimated Number of Previous Interactions with this Healthcare Practitioner

Date of Most Recent Prior Interaction (if applicable)

Has this Healthcare Practitioner previously asked off-label questions about our products?

 

Please describe previous off-label inquiries, including topics and approximate dates:

2. Section 2: Nature of Clinical Inquiry & Specific Molecule/Drug - Detailed Product and Question Characterization

This section documents the specific pharmaceutical product and the precise nature of the clinical inquiry. Accurate and detailed capture of the question is essential for medical affairs to provide scientifically accurate, compliant, and clinically relevant responses. Include all relevant clinical context that may impact the response.

 

Product Brand Name (if applicable)

Product Generic/Scientific Name

Product Strength/Formulation

Product's Currently Approved Indication(s) in this Country (select all that apply)

Nature of the Clinical Inquiry

Specific Off-Label Indication or Clinical Scenario Being Discussed (if applicable)

Verbatim Clinical Question as Stated by Healthcare Practitioner

Did the Healthcare Practitioner provide specific patient case details?

 

Please summarize patient case details (de-identified): age group, disease stage, prior therapies, comorbidities, and specific clinical challenge:

Type of Clinical Information Requested (select all that apply)

Did the Healthcare Practitioner reference specific clinical studies, publications, or data sources?

 

Referenced Studies/Publications

Study/Publication Name

Journal/Conference

Year

Key Finding Referenced

A
B
C
D
1
 
 
 
 
2
 
 
 
 
3
 
 
 
 
4
 
 
 
 
5
 
 
 
 
6
 
 
 
 
7
 
 
 
 
8
 
 
 
 
9
 
 
 
 
10
 
 
 
 

Is this inquiry related to a pediatric, pregnant, or lactating patient population?

 

Specific vulnerable population

Additional Clinical Context or Background Information Relevant to the Inquiry

3. Section 3: Unsolicited Request & Compliance Verification - Regulatory and Policy Adherence Documentation

This critical section documents the unsolicited nature of the request and verifies compliance with company policies and regulatory requirements. Off-label information may only be provided in response to unsolicited requests. Any indication that the question was prompted or solicited by the field representative must be immediately escalated. Complete this section with utmost accuracy.

 

CONFIRMATION: Was this clinical inquiry completely unsolicited and initiated solely by the Healthcare Practitioner?

 

Thank you for confirming. Please continue to document the spontaneous nature of the request in the following questions.

 

CRITICAL: Describe in detail how the question was solicited or prompted. This constitutes a serious compliance violation that must be immediately reported to your manager and compliance department. Do NOT proceed with this intake form until you have spoken with compliance.

How did the Clinical Inquiry Arise? (Select the most appropriate description)

Did you discuss the product's approved indication(s) with the Healthcare Practitioner BEFORE the off-label question was asked?

 

Briefly describe the on-label discussion that preceded the off-label question:

Did you proactively mention, suggest, or allude to any off-label uses of the product?

 

CRITICAL COMPLIANCE ISSUE: Describe exactly what off-label information was proactively shared. This must be escalated immediately to compliance.

Did you provide any promotional materials (visual aids, brochures, leave-behinds) during this interaction?

 

List all promotional materials provided. Note: Providing promotional materials during an off-label discussion may raise compliance concerns.

Did you make any promises or commitments regarding specific answers, timelines, or outcomes to the Healthcare Practitioner?

 

Describe the specific commitment made. Medical affairs will assess if this can be honored within compliance guidelines.

Did you reference any internal, confidential, or unpublished data during the discussion?

 

Describe the internal data referenced. Sharing unpublished data may require additional approvals.

Provide a Detailed Narrative of the Conversation Flow Leading to the Clinical Inquiry

I attest that this clinical inquiry was entirely unsolicited, initiated by the Healthcare Practitioner without any prompting, suggestion, or encouragement from me. I have accurately documented the interaction to the best of my ability and understand that any misrepresentation may result in disciplinary action.

I confirm that I did not proactively share any off-label information, make any inappropriate promises, or provide promotional materials specifically about off-label uses.

4. Section 4: Urgency Assessment & Preferred Response Methodology - Prioritization and Communication Strategy

This section enables appropriate triage and resource allocation by medical affairs. Accurate urgency assessment ensures patient safety concerns are addressed immediately while routine inquiries receive appropriate attention. Specify communication preferences to facilitate effective knowledge transfer.

 

Urgency Level Assessment

Rationale for Urgency Assessment

Does this inquiry involve a potential serious adverse event or product safety concern?

 

URGENT: If this involves a potential serious adverse event, you must IMMEDIATELY report this to the Drug Safety/Pharmacovigilance department through the designated safety reporting channel BEFORE submitting this form. This form is NOT a substitute for adverse event reporting.

Is there an active patient waiting for treatment decision based on this information?

 

When is the patient scheduled for treatment/clinical decision?

Healthcare Practitioner's Preferred Response Method

Should Medical Affairs communicate directly with the Healthcare Practitioner or through the Field Representative?

Healthcare Practitioner Preferred Contact Information for Response

Healthcare Practitioner Availability for Follow-up Discussion (if applicable)

Will additional stakeholders need to be included in the response?

 

Select additional stakeholders to include

Healthcare Practitioner's Requested Response Date (if specified)

Additional Context to Support Appropriate Response Delivery

5. Section 5: Medical Affairs Review & Escalation Approval - Internal Routing and Assessment

This final section captures the field representative's assessment to guide internal medical affairs handling. Your input helps ensure appropriate reviewer assignment, priority setting, and identification of potential issues requiring escalation to specialized teams or leadership.

 

Field Representative Recommended Priority for Medical Affairs Review

Recommended Medical Affairs Reviewer Specialty

Does this inquiry require escalation beyond standard medical affairs review?

 

Select all escalation categories that apply

Have we received similar unsolicited off-label inquiries from other Healthcare Practitioners recently?

 

Describe the pattern, frequency, and nature of similar inquiries. This may indicate emerging off-label use trends requiring broader medical affairs strategy.

Are there any attachments or supporting documents to include with this intake?

 

Upload supporting documents (HCP business card photo, conference agenda, relevant literature, etc.)

Choose a file or drop it here
 

Field Representative Additional Notes for Medical Affairs Reviewer

Field Representative Digital Signature - Attesting to Accuracy and Compliance

Form Submission Timestamp

I have reviewed all information entered for accuracy and completeness. I understand that incomplete or inaccurate submissions may delay the medical affairs response and could compromise compliance. I have reported any safety concerns through appropriate channels and have not included any patient-identifiable information in this form.

To configure an element, select it on the form.

To add a new question or element, click the Question & Element button in the vertical toolbar on the left.